Impact of High Frequency Electromagnetic Fields on Process of Angiogenesis

摘要

The facts about the effects of high frequency electromagnetic fields (HF EMF) on human health are often controversial and incomplete. For this reason, the aim of this study was to examine impact of HF EMF on process of angiogenesis in eight rat organs of: pancreas, kidney, thyroid, liver, cerebrum, thymus, gastric gland and spleen. Wistar strain rats were exposed to HF EM fields with the following characteristics: 1.9 GHz frequency, 0.24 A/m intensity, electric field strength of 4.79 V/m, and SAR (specific absorption rate) value of 2.0 W/m~2. Exposure time was 7 h per day, 5 days per week, over the course of 60 days. Our experiment was conducted on a total of 20 male rats divided randomly into two equal groups: one group of animals was exposed to HF EM fields as described above whereas, the other group of animals was not exposed to any HF EM fields. In our study histological and stereological analysis shows the results that volume density and number of endothelial cells of blood vessels increased with statistical significance in all organs of rats that were exposed to the HF EMF compared to the unexposed group. Increase in volume and number of endothelial cells in analyzed organs indicates the process of angiogenesis induced by HF EM fields, which can be used for therapeutic protocols.