An investigation of color stability and fluorescence behavior of ubiquinone solutions

摘要

Antioxidants, reactive oxygen species and other radicals are involved in oxidative stress phenomena. There are many available methods to quantify the progress of the process and evidence its existence for each stage of oxidative damage process which can be classified into direct and indirect approaches. The technic of experimental determination of optical characteristics stability of antioxidant solutions with spectroscopic method was offered in this work as a direct method for investigation of color stability in time and fluorescence behavior of antioxidant solutions. Coenzyme Q10, or ubiquinone, in the form of oil and alcohol solutions was chosen as an antioxidant of research. The experimental results connected with the optical density and color characteristics confirm the possibility of applying the clinical diagnosis method of estimation redox potential. Also, future prospects, including application of this technic in pharmaceutical analysis for quality control, were discussed.