首页> 外文会议>NATO Advanced Research Workshop on Nanomaterials for Security >Chapter 23 Cerium Dioxide CeO_(2-x) and Orthovanadate (Gd_(0.9)Eu_(0.1)VO_4) Nanoparticles for Protection of Living Body from X-Ray Induced Damage
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Chapter 23 Cerium Dioxide CeO_(2-x) and Orthovanadate (Gd_(0.9)Eu_(0.1)VO_4) Nanoparticles for Protection of Living Body from X-Ray Induced Damage

机译:第23章二氧化铈CEO_(2-X)和脱芳酸盐(GD_(0.9)EU_(0.1)VO_4)纳米粒子,用于保护生物体免受X射线诱导的损伤

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The effectiveness of CeO_(2-x) and GdEuVO_4 nanoparticles in radioprotection in model animals during radiation exposure has been shown. Nanoparticles were injected per os by two different schemes – once and during 15 days. For the 15-days scheme of GdEuVO_4 nanoparticles injection during 30 days of observation the survival of animals irradiated with a dose of 6.0 Gy was 100 %; for ceria it was 90% for ceria. It was revealed that 7.0Gy radiation dose is lethal. These results can serve as a motivation to consider inorganic nanoparticles as the basis for new drugs possessing by radioprotective effect.
机译:已经显示出CEO_(2-X)和GDEUVO_4纳米粒子在辐射暴露期间在模型动物的放射辐射中的有效性。每种OS通过两种不同的方案注射纳米颗粒 - 一次和15天。对于在30天观察期间Gdeuvo_4纳米粒子注射的15天方案,用剂量为6.0Gy照射的动物的存活率为100%;对于Ceria来说,它为Ceria为90%。据透露,7.0gy辐射剂量是致命的。这些结果可以作为考虑无机纳米颗粒作为通过放射保护作用具有新药的基础的动机。

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