A ~1H NMR-BASED METABOLOMIC APPROACH ON DIETARY BIOMARKER RESEARCH IN HUMAN URINE

摘要

The term 'metabolomics' is frequently used to define "the comprehensive analysis of the whole metabolome under a given set of conditions" [1]. This definition implies that this 'omic' science is capable of giving an overview of the whole metabolic profile of a specific biological matrix, to wit its 'metabolome'. The analysis of the so-called metabolome has become particularly important in human studies, allowing the identification of typical and atypical metabolites in determined biofluids and tissues. This is clearly fundamental for medical investigations, since it could be possible to assess the presence or absence of certain dieases and syndromes or risk conditions.