Analysis of height growth of Tibetan Adolescent Children living in high altitude area and Serum bone metabolism indexes

摘要

Objective to explore the characteristics of height growth, bone metabolism biochemical indexes and the regulation of hormone of Tibetan puberty Children in different elevation plateau environment and provide basic data for clinical use. Select 1580 people of 12～18 years Tibetan children in Tibet Lhasa and Naqu, and measure the height and the level of serum carboxyterminal propeptide of I type procollagen (PICP) and Bone glaprotein (BGP), growth hormone (GH) and insulin-like growth factor I (IGF-1). Lhasa children were significantly higher than Nagqu children in each age group in height and serum PICP, BGP, GH and IGF-1, and there is statistically significant differences. Height growth peak of Lhasa female is at the age of 12 ～ 13 years, and male is at the age 13 ～ 14 years. Serum PICP, BGP, GH, IGF-1 levels of two groups were significantly decreased with age, and is closely related to height. Height of adolescent Tibetan children in Naqu was significantly lower than that of children in Lhasa, and levels of serum bone formation markers PICP, BGP and GH, IGF-1 can reflect the height growth.