Preliminary toxicology evaluation of Silymarin

摘要

Research silymarin food security through animal experiments. Acute toxicity test, mouse bone marrow micronucleus test, mice sperm abnormality test results were evaluated. Male and female mice by oral maximum tolerated dose (MTD) are more than 20.0g/kg body weight, according to the acute toxicity grading standards, which are non-toxic level. Mouse bone marrow micronucleus test, mice sperm abnormality test and genotoxicity test were negative. Showed that silymarin is a food safety component.