Relationship between the Differences of Odor Detection Threshold Values Measured by Different Methods and Some of the Physicochemical Properties

摘要

amount of sample can enter the nasal cavity depends on the physiochemical characteristics such as distribution, volatility and solubility. It can be suspected that the difference of odor detection threshold (ODT) measured by different methods is related to the physicochemical properties of compounds. To investigate the relationship between ODT differences and the physicochemical properties of compounds, ODT values of four series of organic compounds were measured by triangle odor bag method and gas chromatography and olfactometry method; the results were compared and the absolute differences were calculated. Relationship between ODT differences and the type of functional group and some of the physicochemical properties of compounds was analyzed. The results showed the type of functional group had significant effect on the differences. Certain linear relationships between the logarithmic value of differences and the logarithmic values of saturated vapor pressure and molecular weight were observed.