Protective Antioxidant System Disorders in Myopic Patients Determined in Tear Liquid

摘要

One of the most powerful intracellular antioxidants is glutathione. Connected SH and S-S - groups represent thiol and disulfide bonds in protein structures. Concentration levels of these groups are considered as important link of antioxidant protection. To evaluate protective antioxidant system by the concentrations of free and connected SH and S-S - groups in tear liquid 34 children with myopia of different degree were observed. Free and connected SH and S-S - groups in tear liquid were defined by spectrocolormeter Spekol-210 wave length 356 nm and 412 nm accordingly. It was established that free SH- groups content in tear of children with high myopia was significantly lower than in children of other groups. It confirmed that protective antioxidant system abilities are weakened in myopia and they decrease with myopic severity.