In one study the residual antibacterial activity on keratinocytes of a chlorhexidine and phytosphingosine shampoo was investigated and compared to a shampoo vehicle. Canine keratinocytes were harvested before and after shampooing. The cells were cultured and bacterial growth was compared between the two treatment groups before and after shampooing. No difference was seen between the placebo and active ingredients with regard to the residual antibacterial activity on keratinocytes after shampooing.
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