CyanoFactory Knowledge Base Synthetic Biology A Plea for Human Curated Bio-databases

摘要

Nowadays, life science research is dominated by two conditions: interdisciplinarity and high-throughput. The former leads to highly diverse datasets from a data type point of view while high-throughput yields massive amounts of data. Both aspects are reflected by the byte-growth of public bio-databases and the sheer number of specialised databases or databases of databases (i.e. data warehouses). We provide an insight to the development of a biodata knowledge base (dubbed CyanoFactory KB) targeted to bio-engineers in the field of synthetic biology and exemplify the need for data type specific data curation and cross-linking. CyanoFactory KB is unique in incorporating experimental data from a broad range of scientific methods that are based on one strain of Synechocystis sp. PCC 6803. The knowledge base can be accessed upon request via cyanofactory.hsmittweida.de.