Protein structure prediction using bio-inspired algorithm: A review

摘要

One of the main problems in Bioinformatics is the prediction of protein tertiary structure from its amino acid sequence. This problem is computationally complex and belongs to the NP-hard class. Although these years many algorithms and methods have been introduced, this problem is still an open area for research. In this paper we discuss the most important algorithms like evolutionary algorithms, particle swarm or ant colony optimization and computational methods introduced in this field and their challenges.