Enzymeless glucose biosensor using CuO nanoparticles on amine-functionalized carbon nanotubes

摘要

CuO nanoparticles on amine-functionalized multi wall carbon nanotubes (CuO/A-MWCNTs) were easily prepared by a fixture-reduction method and used for sensing glucose without GOx. The morphology and structure of the CuO/A-MWCNTs were characterized by FESEM, XRD, and ICP for its Cu content. Cyclic voltammetry and chronoamperometery were used to show the electrochemical and electrocatalytic activity of the nanocomposite towards glucose detection. Comparison between bare GCE, CuO/GCE, A-MWCNTs/GCE and CuO/A-MWCNTs/GCE, indicates that CuO/A-MWCNTs modified electrode have the greatest ability to detect glucose with a low detection limit of 1.0 μM and linear range from 100 μM to 1.5 mM. The modified electrode with a simple synthesis procedure can be used for a highly stable enzymeless glucose sensor.