Influences of Florfenicol Used in Aquaculture on Bacteria in Coastal Marine Sediments

摘要

Florfenicol is an effective antibacterial that is widely used in aquaculture farms. The current paper aims to investigate the potential influences of florfenicol on the growth and activities of microorganisms in the sediments of the Dalian coastal area using spiked experiments. The florfenicol resistance of heterotrophic bacteria in the sediment samples from different stations is also analyzed. The results show that florfenicol inhibits the growth and nitrification rates of both ammonia- and nitrite-oxidizing bacteria. Moreover, the sediment samples from stations which previously used florfenicol or other antibacterials had higher percentages of florfenicol-resistant bacteria, indicating that the resistance of heterotrophic bacteria in the sediments developed due to the use of antibacterials.