An Experimental Observation of Calcium Alginate Medical Film Prevents Bone Cement Leakage in PVP

摘要

Using calcium alginate medical film to explore the preventive measures of bone cement leakage in PVP.60 fresh vertebral bones were dissected from pigs(10 months old with average weight 152.5±7.5 kg), and randomly divided into the blank group, the control group and the experimental group, 20 vertebral bones for a group. Eliminated the extra muscles and ligaments and the upper and lower endplates were completely retained. The models of vertebral compression fractures with fissures in front of vertebra were prepared by drilling two holes with a 3.2 mm electric drill from lateral of the junction of the halfway point of parapophysis and the vertical of superior articular process to anterior vertebra along the direction of pedicles of vertebral arches by angle 10 and 15 degree and downward sloping 5 degree with the sagittal planes. Only bone cement was injected to the blank group, while the control group were injected with bone cement after injected medical fibrin glue. And the experimental group were injected with bone cement after injected sodium alginate glue and solidified by saturated calcium chloride. The injection dose of bone cement was recorded when bone cement leaked. The injection dose of bone cement in experimental group was significantly higher than the blank group and the control group when bone cement leaked (P<0.01). Calcium alginate medical film can effectively prevent the leakage of bone cement in PVP.