Study on Synthesis Technology of Glyoxylic Acid Fine Chemicals

摘要

Glyoxylic acid is an important intermediate of organic chemical and it can generate dozens of fine chemical products. At present, its production process is mostly in the manufacturing of 30% to 50% solution of glyoxylic acid. Due to the presence of large amounts of water, solution of glyoxylic acid in aqueous solution is difficult to meet the needs of medicine, food and other industries which require high-purity crystal glyoxylic acid products. The experiments show that synthesis process using crystal glyoxylic acid as raw material in the manufacturing of allantoin instead of solution of glyoxylic acid is reasonable and feasible. Compared with other synthetic methods reported in the literature, this method has advantages of simple technology and high yielding. Solvent inspection results show that solvent polarity has some influence on the reaction results. That the polarity is too strong and too weak is not conducive to reaction. The mixed solution of tetrahydrofuran and ethanol is suitable reaction solvent.