Iodine-Mediated Efficient Synthesis of 2,3-Dihydro-pyrazines

摘要

The synthesis of 2, 3-dihydro-pyrazines has been developed by an efficient protocol of annulations of 1, 2-diketones and ethylenediamine. A variety of 2, 3-dihydro-pyrazines were prepared in high yields in the presence of a catalytic amount of iodine.