Electrochemical behaviours of scutellarin at multi-wall carbon nanotubes modified glassy carbon electrode

摘要

A multi-wall carbon nanotube modified glassy carbon electrode (MWCNTs/GCE) has been prepared. The electrochemical behavior of scutellarin at the modified electrode and its electroanalytical method have been studied. It was showed that in 0.20 mol/L Na_2HPO_4-NaH_2PO_4 buffer solution (pH=7.4) MWCNTs/GCE exhibited excellent catalytic and enhancement effect on the electrochemical oxidation of scutellarin, the sensitivity increased 23 times compared with that at bare GCE. The measurement parameters were optimized. Under the optimal conditions, the linear range of scutellarin concentration was 4.0×10~(-6) - 1.0×10~(-4) mol/L (R=0.9991) with a detection limit of 8.2×10~(-7) mol/L (S/N=3), and the RSD for 4.0×10~(-5) mol/L scutellarin solution was 1.8% (n=11). This method was successfully used in the determination of scutellarin in injection and tablets.