The Effect of Endosulfan Insecticide On Blood Parameters in Rat

摘要

Endosulfan an insecticide has not vast usage in controlling of insects. This poison is assailable on human and animals via food, aspiration and skin. In this research, checked the long-range effect of Endosulfan EC 35% on blood factors in rat. So 40 rat divided to 5 groups. The control group, the placebo group receipted saline 9% and 3 experimental groups receipted 5 , 10 and 20 mg/kg for 21 days via gavages Endosulfan EC 35%.On the end of experiments the rats wants into comatose via chloroform, phlebotomy of heart done and blood factors evaluated with laboratory standard methods. Statistics analyze shows that the scale of WBC, monocyte, has got increase (P<0.05) and RBC, lymphocyte. Platelet, has got decrease (P< 0.05) toward Control group. Endosulfan on long-range has got important effects on blood factors that can causes of serious hurts and even anemia and correlate malady, in addition the effect ions of chemical poisons depends on dose and tangent time, so increase of using Organochlorea slump-dais in homes and farms for destroying Jassids is dangerous for health of humans and animals.