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Dual Functionalized Janus Nanocomposites for Targeted pH-Responsive Drug Delivery

机译：双官能化Janus纳米复合材料用于靶向pH响应药物递送

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A superparamagnetic Janus nanocomposite (SJNC) of polystyrene/Fe_3O_4@SiO_2 was designed and developed with dual surface bearing functional groups for medical diagnosis and treatment. Folic acid (FA) and doxorubicin (DOX) were conjugated stepwise to the surfaces. SJNCs were found to enable simultaneous cell-targeted drug delivery via pH-responsive release mechanism.

机译：设计和开发了一款超顺磁性Janus纳米复合材料（SJNC）的聚苯乙烯/ Fe_3O_4，并用双面轴承官能团，用于医学诊断和治疗。叶酸（Fa）和多柔比星（DOX）逐步循环到表面上。发现SJCS通过pH响应释放机制能够同时进行细胞靶向药物递送。

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《Materials Research Society Meeting》|2014年||共6页
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Feng Wang; Giovanni Pauletti; Yilong Wang; Donglu Shi;
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中图分类 R318.08-53;
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入库时间 2022-08-21 07:09:53

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1. Dual Surface-Functionalized Janus Nanocomposites of Polystyrene/Fe_3O_4@SiO_2 for Simultaneous Tumor Cell Targeting and Stimulus-Induced Drug Release [J] . Feng Wang, Giovanni M. Pauletti, Juntao Wang, Advanced Materials . 2013,第25期

机译：聚苯乙烯/ Fe_3O_4 @ SiO_2的双表面功能化Janus纳米复合材料可同时靶向肿瘤细胞和刺激药物释放。
2. Dual-functional liposomes based on pH-responsive cell-penetrating peptide and hyaluronic acid for tumor-targeted anticancer drug delivery [J] . JiangT., ZhangZ., ZhangY., Biomaterials . 2012,第36期

机译：基于pH响应细胞穿透肽和透明质酸的双功能脂质体可用于靶向肿瘤的抗癌药物
3. Janus-faced and pH-responsive nanohybrids for synergistic targeted drug delivery [J] . Liu Shucheng, Pan Jianming, Dai Xiaohui, Journal of Controlled Release: Official Journal of the Controlled Release Society . 2017,第期

机译：Janus-Faced and pH响应纳米组织，用于协同靶向药物递送
4. Dual Functionalized Janus Nanocomposites for Targeted pH-Responsive Drug Delivery [C] . Feng Wang, Giovanni Pauletti, Yilong Wang, Materials Research Society Meeting . 2014

机译：双官能化Janus纳米复合材料用于靶向pH响应药物递送
5. Synthesis and Characterization of Janus Particle Nanocarriers and DNA Devices Toward Multifunctional Drug Delivery Systems [D] . Mo, Alexander Han-Chung 2015

机译：Janus颗粒纳米载体和DNA器件的合成和表征，用于多功能药物递送系统
6. Construction of pH-responsive and up-conversion luminescent NaYF4:Yb3+/Er3+@SiO2@PMAA nanocomposite for colon targeted drug delivery [O] . Boshi Tian, Shaohua Liu, Wei Lu, -1

机译：pH响应和上转换发光NaYF4：Yb3 + / Er3 + @ SiO2 @ PMAA纳米复合材料的构建
7. Dual Surface‐Functionalized Janus Nanocomposites of Polystyrene/Fe 3 O 4 @SiO 2 for Simultaneous Tumor Cell Targeting and Stimulus‐Induced Drug Release [O] . Wang Feng, Pauletti Giovanni M., Wang Juntao, 2013

机译：聚苯乙烯/ Fe 3 O 4 @siO 2的双表面功能化Janus纳米复合材料用于同时肿瘤细胞靶向和刺激诱导的药物释放

Dual Functionalized Janus Nanocomposites for Targeted pH-Responsive Drug Delivery

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