A vaccine prototype using baculovirus expression system for the control of Avian Influenza Virus

摘要

Influenza virus causes an important disease worldwide. Avian Influenza LP and HP represent a high risk for poultry producers, and its control is a major burden according to sporadic outbreaks which are related to the distribution of HP variants. The virus causes disease in several continents. The control of AIV, H5 subtype, remains as a main challenge and different kind of vaccines are available. The use of insect cells and baculovirus to produce the H5 HA offers the versatility, simplicity, scale-ability and yields of a very efficient vaccine producing process.