Ehmmation and control of aflatoxincontamination in agricultural crops throughAspergillus flavus genomics

摘要

Aflatoxins are the most carcinogenic mycotoxins produced by Aspergillus flavus and A. parasiticus. The primary objectives of our A. flavus genomics program are to reduce and eliminate aflatoxin contamination in food and feed and control fungal infection in preharvest crops such as corn, cotton, peanut and tree nuts. A. flavus EST and whole genome sequencing projects for this fungus project were completed. Three different types of A. flavus microarrays have been constructed and used in gene profiling and functional genomics studies. In order to control aflatoxin contamination of agricultural crops, genes that are potentially involved in aflatoxin formation and fungal infection have been identified through genomics tools.