Flow System Calibration in Medical and Bio-medical Production Processes.

摘要

The manufacture of drugs or medical equipment requires many complex production operations, none more than the ability to ensure the correct amount of drug is contained in a tablet or deposited on a product. Many items for use within the body, i.e. a stent to open a blocked artery or a pacemaker to control the hearts rhythm require that they are coated in drugs that will stop the human body from rejecting the device. The manufacturing processes of this type of equipment uses Mass Flow Controllers or Mass Flow Meters that can control or measure the amount of drug being deposited within the production process. In the production of incubators or other hardware used for controlling breathing we need to verify the volume flow rate of the air being delivered. Flow meters are used in the production process to verify these parameters. In all cases the production test equipment needs to be periodically calibrated in the most efficient and effective way to ensure minimal production down time. This paper discusses a technique to calibrate gas mass flow and volume flow devices using a commercial mass flow measuring system that has no moving parts, enabling simplification and automation of these tasks within the calibration laboratory.