Biocompatibility research of the biphasic calcium phosphate composite ceramic film obtained through micro-arc oxidation on the medical titanium surfaces

摘要

To obtain optimal medical ceramic film with bioactivity, Microarc oxidized TiO_2-based films containing Ca and P on titanium alloy were formed in electrolytes containing hydroxyapatite and β-tricalcium phosphate salts. After that the biocompatibility tests including invitro soaking test and invivo implant experiment were carried out, and component and phases of films were analysed by energy dispersive spectrometer and X-ray diffraction, respectively. The obtained result shows the porosity biomedical ceramic films with different proportional of Hydroxyapatite/β-tricalcium are fabricated through changing the electrolyte composions, respectively. The bioactivity of biphasic calcium phosphate is enhanced comparing to the pure HA ones. So the biphasic calcium phosphate film material can be satified with medical application.