IMMUNOGENICITY ANALYSIS AMONG HLA ANTIGENS FROM THE ALLOANTIBODY PROFILE OF PATIENTS WITH SENSITIZED EVENTS

摘要

HLA antigen's immunogenicity is important for alloantibody production. Although organ rejection could be caused from several different reasons, antibody-medicated rejection is important cause of graft failure. Some of HLA antigens have higher immunogenicity than others. So, HLA mismatch with lower immunogenicity may have higher graft survival. This study will focus on analyzing the HLA antigen immunogenicity from sensitized patients on the waiting list for kidney transplantation at Montefiore Medical Center, New York.