The treatment of chloasma is one of the most challenging ones for a dermatologist. As it occurs widely in the human population it is of broad interest for control. Hypothetically, the condition is self-limited. However spontaneous resolution is time-consuming, unpredictable and may take months to years to resolve normal pigmentation.The major problems in treating chloasma are the prolonged time to response, the inconsistency of response to treatments, the unpredictability regarding the result after any procedure and the substantial relapse rate when the therapy is discontinued. Treating this dyschromia is also challenging because of the feared postinflammatory hyperpigmentation after inflammation-inducing therapies.
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