A case of cutaneous lipoid proteinosis is report. A 67-year-old male presented with a 4-year history of skin lesions on the lower extremities and a more than 3-year history of skin lesions on the face and hands. Physical examination revealed ivory white to light yellow, beaded, linear lesion on the face, verruciform papules on the hands, and ichthyosis-like lesions on the lower extremities. The case was diagnosed as lipoid proteinosis, according to the clinical manifestations and the histopathologi-cal findings, especially positive PAS staining. However, the onset in old age and the dermal infiltration of neutrophils of this disease were quite different from the typical cases of lipoid proteinosis, the patient is under close follow up.
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