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Integration and characterization of SiN nanopores for single-molecule detection in liquid-core ARROW waveguides

机译:液体箭头波导中单分子检测的SIN纳米孔的整合与表征

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We demonstrate a method for integrating silicon nitride nanopores in liquid core Anti Resonant Reflecting Optical Waveguides (ARROW) for single molecule electrical detection and control. We use a two-step integration process when a micropore is fabricated first, paving the way for subsequent nanopore integration in the first silicon nitride layer of the ARROW structure. Nanopores with dimensions as small as 11 nm were fabricated using a Focused Ion Beam shrinking process commensurate with single particle gating of viruses, proteins, ribosomes and other biomolecules.
机译:我们证明了一种用于将氮化硅纳米孔与反射光波导(箭头)的氮化硅纳米孔集成,用于单分子电检测和控制。 首先制造微孔时,我们使用两步集成过程,为箭头结构的第一氮化硅层中随后的纳米孔集成铺平道路。 使用尺寸小至11nm的纳米孔使用聚焦离子束收缩工艺与病毒,蛋白质,核糖体和其他生物分子的单粒子栅相相称。

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