Coffee is quite popular of the leisure drink, and the ingredients of coffee include caffeine, aroma, protein, tannic acid and fat et al. The references show a small amount of caffeine can stimulate the brain and enhance memory, if caffeine is over the amount that heart, high blood pressure, kidney and coronary artery would be caused a negative impact. In this paper, we use the special ultrasound method with high-frequency, well penetrating power and the sound wave to extract the caffeine. And also, a new extraction equipment is designed to make the coffee powder and extraction liquid of water mixed efficiently. The different operating conditions for extraction experiments are executed and the obtained results are also compared. The results show that caffeine has already reached the saturated condition at 15 second of extracting time and the quantity of caffeine is increased with temperature raised. However, the influence of vibration frequency is not significant.
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