Fiber-based Raman Spectroscopy of Glucose

摘要

Design and functionality of a reagent-free Raman-based fiber optic sensor are described in the context of glucose monitoring. Theoretical calculations of sensor performance are shown using raytrace software. An optimized sensor design with an outer diameter of 1.5 mm was carried out. First experiments in aqueous glucose solutions showed a root mean square error of prediction of 10.5 mg/dl in an independent validation.