Assembly of Bioreducible Layer- By-Layer Films for Sequential DNA Delivery(PPT)

摘要

1. Exponential growth LbL film leads to bulk erosion 2. Linear growth LbL film leads to surface erosion 3. Periodic insertions of PEI 3.1 Film growth changes from exponential to linear. 3.1 Film disassembly changes from fast releasing to slow and sustain releasing 4. Obtain slow and sequential DNA release with nanometer size particles. 5. Successful DNA delivery in vitro