Functional monitoring of a living tissue at its clearing

摘要

Principles of optical clearance are discussed. Results of simulations of diffraction of laser beam by a small blood vessel, imbedded in scattering tissue, are presented. Influence of optical clearance of scattering tissues on the results of Doppler diagnostics is considered. Doppler shift of intensity fluctuations of scattered light is investigated as a function of laser beam radius, radius of blood vessel, depth of the vessel in the tissue and scattering characteristics of flowing blood.