Novel Amphiphilic Triblock Copolymer Poly(methoxyethylene glycol)-b-Poly(L- lactide)-b-Poly(L-lysine) for Enhancement of Osteoblast Attachment and Growth

摘要

Tissue engineering holds great promise for the millions of patients who suffer tissue loss or organ failure. One approach to replacing lost tissue function is to attach mammalian cells to natural or synthetic matrices and implant the resulting device. A critical challenge to this approach is developing suitable matrix materials, because cell function and viability are greatly affected by the substrate.