THE INFLUENCE OF MICROSTRUCTURE IN THE FABRICATION AND ELECTROPOLISH FINISH OF CORROSION RESISTANT EQUIPMENT FOR THE BIOPHARMACEUTICAL INDUSTRY

摘要

With today's emphasis on process and product safety and compliance to Federal Regulations such as Title 21, CFR 211.65, selection of suitable materials of construction for the bio-technology and pharmaceutical industries is a critical step in designing or modifying plant equipment. Selecting the material of construction is only the first step, ensuring that the selected material meets the metallurgical and corrosion resistance performance that is expected is a very important second step. This paper discusses the reason for the high quality microstructural requirements for equipment destined for the bio-pharmaceutical industry. This paper also discusses some of the problems that have been encountered during the fabrication of high performance corrosion resistance equipment and provides guidelines to ensure that the equipment meets the required expectations.