Laboratory and field trials with thermostable live Newcastle disease vaccines in Mozambique

摘要

The Australian strains of avirulent, thermostable Newcastle disease virus designated NDV4-HR and I-2 were tested in the laboratory and under field conditions in Mozambique. An overview of this work is presented. Under experimental conditions, both vaccine strains provided protection to all vaccinated birds and those in contact with them against a local virulent strain of ND virus, V868. Field trials confirmed these results. In addition, it was shown that vaccine administered by eye-drop gave better results than vaccine administered in the drinking water or by oral drench. There were no adverse reactions to the vaccines and it was concluded that NDV4-HK and I-2 strains are avirulent, innocuous, efficacious, immunogenic and suitable for use in the control of ND in Mozambique. Factors contributing to the successful implementation of the field trials are. also discussed.