Analysis of poly(dA) · poly(dT) structure by Raman spectroscopy and lattice dynamics

摘要

Raman spectrum of poly(dA) · poly(dT) in 0.2M NaCl solution was recorded over the spectral range 750-1000 cm~(-1). Normal mode analysis of heteronomous secondary structure from poly(dA) · poly(dT) fibers was carried out by the lattice dynamics. The calculated frequencies are good agreement with the observed Raman spectrum. This indicated that poly(dA) · poly(dT) in solution probably has the same structure as poly(dA) · poly(dT) fiber.