Simeconazole (F-155), a novel systemic fungicide with broad-spectrum activity for seed treatment

摘要

Simeconazole, 2-(4-fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-trimethylsilylpropan-2-ol, is a novel triazole fungicide with prominent systemic effects and good crop safety. It shows broad and strong antifungal activity against plant pathogens, especially those of the Basidiomycetes. Seed treatment with simeconazole achieves excellent efficacies against wheat loose smut (Ustilago nuda) at doses of 4-10 g a.i./100 kg seed. At high doses of 50-100 g a.i./100 kg seed, the controlled-release formulation of simeconazole is also effective against soil and airborne diseases such as sharp eyespot (Rhizoctonia cerealis), eyespot (Pseudocercosporella herpotrichoides), and powdery mildew (Blumeria graminis). Simeconazole increases wheat yield by approximately 10 percent over untreated control crops.