Computer simualtions for microchip electrophoresis

摘要

A mathematical model describing electrokinetically driven mass transport phenomena in microfabricated chip devices is presented. The model accounts for principal material transport mechanisms including electrokinetic migration (electrophoresis and electroosmosis) and diffusion. A computer code that implements the model is capable of simulating the mas transport during electrokinetic manipulation in any 2-D channel structures. The code allows arbitrary channel geometries with various boundary conditions for the electric field and the sample concentration. The results simulating the sample mass transport in a cross channel geometry during different types of electrokinetic injection are presented.