Real-time monitoring of immunology reactions using computer-aided phase microscope

摘要

The main advantages of the computer-aided phase microscope (CPM) Airyscan which permits the user to observe the cell surface and internal structure consists in superresolution and the possibility of the dynamic processes registering. Immunocompetent cells in process of activation with different agents were studied. Several criterions for evaluation of the functional status of immunocompetent cells based on the shape changes were suggested on the basis of real-time immunology reaction monitoring. The perspectives of the proposed method for immunology testing are discussed.