Temperature distributions in laser-irradiated tissues

摘要

Continuous wave (cw) hydrogen fluoride (HF) chemical laser interactions with human corneal tissue have been studied in order to understand tissue heating phenomenology, effects, and mechanisms under well- characterized laser irradiation conditions. Time-resolved tissue front surface temperature measurements have been obtained during laser irradiation using an optical pyrometer system. Both front surface and in-depth temperature distributions have been calculated by 1D and 2D heat transfer models using realistic tissue optical and thermal properties data for comparison with experiment. The combined experimental/modeling results are useful for developing safe and effective laser microsurgical heating procedures.