Swelling Behavior and Antibacterial Property of Sericin/NIPAAm/AgNPs Semi-IPN Hydrogel

摘要

In order to explore the application of hydrogels in drug release, sericin/PNIPAAm/AgNPs hydrogels were prepared using semi-interpenetrating polymer network technology in this experiment. The results were showed that under the lower critical solution temperature, PNIPAAm was more hydrophilic than SS. When the temperature was more than the lower critical solution temperature, the hydrogen bond which formed between sericin and PNIPAAm has partially limited the shrinkage of PNIPAAm. The bacterial reduction of the hydrogels against Staphylococcus aureus and Escherichia coli were 87% or more.