We performed thermal imaging studies of 229 brain tumor patients with various histology during neurosurgery. We formulated principles of dynamic infrared mapping of exposed cortex and demonstrated that this approach reflects the spatial distribution of cerebral blood flow determined by autoregulation activity. This is the first detailed investigation of spatial temperature dynamics in the peritumoral area and the first assessment methodology for the autoregulation reserve of the peritumoral pial-capillary bed. A specificity of the spatiotemporal dynamics of the cortex thermal pattern in response to the developed effective cold test, depending on the degree of brain tumor malignancy grade, is proved.
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