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Morphogenetic and Homeostatic Self-assembled Systems

机译:形态发生和稳态自组装系统

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As a natural evolution of developments in membrane computing and self-assembly, the time appears ripe to hybridize their principles to explore models capable of exhibiting further properties exhibited by living organisms, while preserving the primary advantages of models in physics, chemistry and computer science, e.g. arising from local interactions of their components and implementable in silico and/or in vitro. We introduce an abstract model named M system, capable of self-assembly and a developmental process, that strikes a balance between these conflicting goals, namely biological realism, physical-chemical realism and computational realism. We demonstrate that such systems are capable of being assembled from scratch from some atomic components, undergo a process of morphogenesis by the unfolding of the self-assembly rules defined by their local interactions, exhibit crucial properties of living cells as the self-healing property or mitosis (cell division), and eventually enter a stable equilibrium of adulthood in which they will continue to function as long as certain conditions in their environment remain. We present some theoretical results on the model, as well as preliminary simulations and experimental results of an M system simulator we have developed to explore this kind of model.
机译:由于在膜的发展计算自然进化和自组装,时间显示成熟杂交自己的原则探索能够表现出由活的生物体表现出进一步的性质的模型,同时保留在物理模型的主要优点,化学和计算机科学,例如由其组分的局部相互作用产生,可在硅和/或体外实现。我们介绍了一个名为M系统的抽象模型,能够自组装和发展过程,这些过程之间存在平衡,即生物现实主义,物理化学现实主义和计算现实主义。我们证明这种系统能够从某些原子成分从划痕组装,通过展开由其局部相互作用定义的自组装规则的形态发生过程,表现出活细胞作为自我修复性质的关键特性或有丝分裂(细胞分裂),最终进入成年期的稳定平衡,只要环境中的某些条件仍然存在,它们将继续运行。我们在模型上提出了一些理论结果,以及M系统模拟器的初步仿真和实验结果,我们开发用于探索这种模型。

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