Physicochemical Characterization of Nano-Hydroxyapatite Prepared by a Wet Method

摘要

Recently nano-hydroxyapatite (nano-HA) has been used as a new biomaterial in medical and dental fields. There are many methods to synthesize the nano-HA. In the present study, the nano-HA was synthesized under various reaction conditions by a wet method using neutralization reaction of calcium hydroxide suspension and phosphoric acid solution. The physicochemical properties of the nano-HA were characterized by XRD, FTIR, TG and TEM. The XRD, FTIR and TEM results indicated that the nano-HA samples were pure and had a plate-like morphology with a size of less than 50 nm in the width. Though all samples contained carbonate, the contents were determined to be 2-4% by TG. The crystallinity of the nano-HA prepared at a body temperature of 37 °C increased higher than that at a lower temperature of 7-10°C.