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A case study: Oral Pro Vitamin D3 plus E to aid in control of PRRS virus circulation in three sow farms

机译:一个案例研究:口服亲维生素D3加上e帮助控制三个播种农场的PRRS病毒循环

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Porcine reproductive and respiratory syndrome virus (PRRSv) has been infecting sows and pigs on farms for decades. Sometimes a producer will decide to eliminate it by depopulating, cleaning the premises, and starting over with a source of negative gilts. Unfortunately, this negative herd is just as susceptible as the previous herd. Sometimes it is better to just learn how to live with the virus. Being infected by one strain of PRRSV may not provide much protection when a different strain infects theanimals. For some producers, the goal is not to eliminate PRRSV. Rather, the goal is to live with it and wait for herd immunity to develop resulting in production of PRRSV-negative offspring. Instead of waiting, the producer may want to intervene in an attempt to shorten the time-to-negative-pig (TTNP) interval. A recent study looked at TTNP using herd closure and intervention with virulent resident virus (LVI) or MLV vaccine.1 Measuring from the first day that intervention was administered, researchersfound the median TTNP was 27 weeks across both interventions and the range was 12 to 43 weeks. Herds using LVI reached TTNP significantly (P < 0.05) earlier than those using MLV (median 25 weeks and 33 weeks respectively). Additionally, herds with a history of previous outbreaks reached TTNP about 9 weeks sooner as compared to naive herds breaking for the first time. It can take a long time between PRRSV outbreak in a sow herd and producing negative pigs. Any intervention that will help reduce the TTNPrepresents real economic gain for the producer and an improvement in the health and welfare of the animals.
机译:猪繁殖与呼吸综合征病毒(PRRSV)已感染农场母猪和仔猪数十年。有时,生产者将决定由人口减少,清洁的场所,并与负母猪源重新开始消除它。不幸的是,这畜群负是一样容易受到上一去就行了。有时,最好是刚刚学会如何用病毒活。由PRRSV的一个菌株感染可能无法提供更多的保护,当不同的菌株感染theanimals。对于一些生产商,我们的目标不是消除PRRSV。相反,我们的目标是生活并等待群体免疫发展导致生产PRRSV阴性的后代。而不是等待,制片人可能希望在试图缩短时间到负猪(TTNP)间隔进行干预。最近使用牛群关闭和干预剧毒居民病毒(LVI)或MLV vaccine.1从第一天介入给予测量看着TTNP研究,researchersfound平均TTNP是27周在两个干预和范围为12〜43周。畜群使用LVI显著达到TTNP(P <0.05)早于使用MLV(中位数25周和33周)的那些。此外,相比于幼稚存栏突破首次牛群与以往爆发的历史达到大约9周越早TTNP。它可以在一个母猪PRRSV的爆发和产生阴性猪之间的很长一段时间。任何干预,这将有助于减少对生产者的TTNPrepresents真正的经济增长和在动物的健康和福利的改善。

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