Itaconic Acid Based Hybrid Hydrogels. Controlled Release of Silver Ion and Antimicrobial Activity Studies

摘要

Hydrogels are polymeric biomaterials of three-dimensional porous structure similar to living tissues. It is easily to embed therapeutic agent in order to design a hybrid biomaterial for biomedical and bioengineering applications [1, 2]. Notably, comparing to all other available antimicrobial agents, silver is probably the most powerful antimicrobial therapeutic agent that exhibits a strong toxicity toward a broad range of microorganisms, and simultaneously a remarkably low human toxicity [3].