Novel Membranes for Hydrophobic Interaction Chromatography

摘要

Responsive membranes have been developed for hydrophobic interaction chromatography. Poly N-vinylcaprolactam (PVCL) chains were grown from the surface of regenerated cellulose membranes using atom transfer radical polymerization (ATRP). Modified membranes were characterized using scanning electron microscopy, infrared spectroscopy, X-ray photoelectron spectroscopy contact angle. ATRP allows us to independently control chain density and molecular weight. The grafting degree of PVCL increases with increasing ATRP initiator immobilization time.