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Enhanced migration of Mesenchymal stem cell spheroids towards glioma

机译:增强间充质干细胞球体对胶质瘤的迁移

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MSC spheroids were prepared using a microfluidic device in as small as 4 hrs. These MSC spheroids showed higher expression of CXCR4 and enhanced migration towards tumor cells. Hence MSC in spheroidal form are an excellent candidate for treating glioblastomas. In the future these spheroids will be transduced with TRAIL and evaluated as a potential drug carrier for treating glioblastomas.
机译:使用小于4小时的微流体装置制备MSC球体。这些MSC球体表达了较高的CXCR4表达和对肿瘤细胞的增强迁移。因此,球形形式的MSC是治疗胶质母细胞瘤的优异候选者。将来,这些球形将通过痕迹转导,并评估为治疗胶质母细胞瘤的潜在药物载体。

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