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Enhancement of integrin-mediated cell attachment by pre-adsorbed model proteins on poly(NaSS)-functionalized Ti6Al4V susbstrates: a QCM-D study

机译:通过预吸附的模型蛋白在聚(NASS) - 官能化Ti6Al4V Susbstration上提高整联蛋白介导的细胞连接:A QCM-D研究

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Presence of sulfonate groups favored protein adsorption and cell attachment. On these altered surfaces, integrin-mediated attachment was predominant and played a major role in cell cytoskeleton organization. Poly(NaSS) was also found to have a large influence on Fn protein conformation, exposing more active binding sites.
机译:磺酸盐基团的存在有利于蛋白质吸附和细胞附着。在这些改变的表面上,整联蛋白介导的附着是主要的并且在细胞细胞骨架组织中发挥了重要作用。还发现聚(NASS)对Fn蛋白质构象的影响很大,暴露更多的活性结合位点。

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