Engineered Dermal Micro-Tissues For Bottom-Up Tissue Engineering And TOC Applications

摘要

In conclusion, our results show that the μTPs are living micro tissue elements that evolve their properties during culture time mimicking different status of a native tissue. Main peculiarity of our μTPs appear to be the endogenous collagen, this feature makes them different from conventional in vitro tissue model and permits testing a large number of drugs and drug combinations in a well-replicate micro-scale human tissues equivalent.