Retinal detachment is an eye disorder that, if not treated, can lead to blindness. One of the treatment options is removing all or part of vitreous humor from the vitreous cavity and filling it with a gas bubble. The gas bubble eventually reabsorbs over a few weeks into the systemic circulation. If patients with an intraocular gas bubble travel to high altitude, they may experience discomfort, headache, and/or loss of vision due to increased intraocular pressure (IOP). The strong increase in IOP may damage the optic nerve head and lead to blindness. Experimental measurements [1, 2] have also shown that in presence of an intraocular gas bubble, IOP rises when altitude increases. In this study, we used a mathematical model to simulate elevation-induced changes in IOP with different sizes of the intraocular gas bubbles.
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